Determination of in-vitro equivalence of paracetamol tablets
نویسندگان
چکیده
منابع مشابه
Spectrophotometric Determination of Promethazine Hydrochloride and Paracetamol in Pharmaceutical Tablets
Spectrophotometric techniques were developed for the determination of single and binarymixture Promethazine hydrochloride (PMH) and Paracetamol (PCM). Normal and first derivative (D) used for single drug at λ 249.5 and 243.0 for PMH and 243.5 and 225 for PCM. The simultaneous determination of binary mixture (PMH) and (PCM) were accomplished by first derivative (D) and second derivative (D) spec...
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15 صفحه اولBioequivalence study of paracetamol tablets: in vitro-in vivo correlation.
The bioequivalence of three chemically equivalent paracetamol generic Mexican products (500 mg tablets) was evaluated in 12 healthy volunteers using the American innovator product (Tylenol, McNeil, Fort Washington, PA), as the reference. Single oral doses of each product were administered at 1-week intervals using a 4 x 4 Latin square design balanced for the first residual effect. The total amo...
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ژورنال
عنوان ژورنال: International Journal of Multidisciplinary Studies
سال: 2014
ISSN: 2465-6380,2362-079X
DOI: 10.4038/ijms.v1i1.41